RESEARCH,
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Welcome to Cynthia Gregg MD | Face & Body Specialists

Welcome to our practice! CYNTHIA GREGG MD, FACE & BODY SPECIALISTS, has been providing plastic surgery and aesthetic services to patients in Cary, Raleigh, the surrounding areas of North Carolina, and across the nation for over twenty years.

Founded by Dr. Cynthia M. Gregg, the practice has treated thousands of patients with both surgical and non-surgical procedures with excellent results. Dr. Cynthia M. Gregg established a culture of trustworthiness and mutual respect that encompasses both employees and patients. The practice is staffed by professional, ethical, giving and compassionate individuals who are committed to their patients, profession, and communities.

We are pleased that you are considering our practice for your cosmetic enhancement or reconstructive services. Our entire staff is available to assist you in realizing your aesthetic goals in our safe, accredited, state-of-the-art facility.

Welcome to
Cynthia Gregg MD, Face & Body Specialists

Our Board Certified Facial Plastic and Reconstructive Surgeon, Aesthetic Nurse Injectors, and Licensed Aestheticians are ready to help you meet your aesthetic goals.

MEET YOUR SURGEON

PROCEDURES

Dr. Cynthia M. Gregg and her licensed, credentialed, and highly experienced clinical providers help patients restore confidence and a sense of self by providing natural-looking enhancements to their faces and bodies.

SPECIALS

Discounts on products, services, and more!

CONTACT US

Schedule a consultation with our Board Certified Facial Surgeon, Aesthetic Nurse Injectors, or Licensed Aestheticians

ASK THE SURGEON

Real questions from patients, real answers from our board-certified surgeon

TESTIMONIALS

Hear what our patients have to say

Our Surgeon

Cynthia M. Gregg MD, FACS

FACIAL PLASTIC SURGEON

Dr. Cynthia M. Gregg is a fellowship trained facial plastic and reconstructive surgeon.

Read more…

Our Procedures

July/August SPECIAL

Get beautiful, glowing skin and a COMPLIMENTARY Alastin® Reset Kit of travel products that are perfect for your upcoming vacations – truly a Win-Win for summer!

Purchase 2 AquaGold® facials and receive an Alastin® zipper bag containing the Reset Kit of products, travel-size HA Immerse Serum, Hydratint Pro-Mineral Sunscreen, and C-Radical Defense Antioxidant Serum!

AquaGold® is the perfect treatment for summer. Our Aestheticians infuse hydrating serum(s) into your skin with a 24K gold delivery system to stimulate collagen and provide an immediate glow. This is a perfect summertime treatment as there is no downtime and no sun exposure restrictions, just dewy, glowing skin!

*While supplies last

Walk in with parched skin – walk out with glowing, hydrated skin!

Blog

How Airessence Pure PDGF+® Is Expanding Our Non-Surgical Toolkit

For many years, the foundation of non-surgical facial rejuvenation has relied on two treatment modalities: neurotoxins to soften the lines caused by muscle movement, and dermal fillers (HA) to restore lost volume and structure. Both are safe, effective, and trusted.

We now have an additional regenerative treatment modality that includes PDGF+® (Platelet-Derived Growth Factor). Rather than relaxing muscles or adding volume, biostimulators, such as PDGF+®, stimulate your tissue to rebuild itself. We see it not as a replacement for neurotoxins or fillers, but as a component in a comprehensive, layered approach to facial aging.

What Is Ariessence Pure PDGF+®

PDGF+® is a cosmetic product consisting of proprietary, pure, recombinant, sterile platelet-derived growth factor (PDGF) with a proprietary blend of sterile hyaluronic acid (HA) for topical use, designed to improve the appearance of the skin. This naturally occurring protein found in platelets and various other cells plays a central role in your body’s healing process, signaling cells to generate new collagen, rebuild blood vessel networks, and repair damaged tissue. PDGF+® targets specific cellular mechanisms, making it a potent and predictable agent for skin rejuvenation. It is not intended to treat, diagnose, or prevent any disease, or affect the structure of the human body.

The version used in aesthetic medicine is a lab-generated, pharmaceutical-grade form, which allows for a precise, consistent dose every time. PDGF+® has an established medical safety record of over two decades, with four FDA approvals for regenerative applications, including diabetic wound healing and bone/tissue regeneration. Its use in facial aesthetics is a newer, growing application of that same well-studied biology. It is listed with the FDA as a Cosmetic Product (Listing Number 53-171423-311193). As with all Cosmetic Products, FDA pre-approval is not required.

Rather than competing with neurotoxins or fillers, PDGF+® fills a gap that neither can address on its own – the quality of the tissue itself. Fillers can restore volume, neurotoxins can relax muscles to soften wrinkles, but neither improves the thin, fragile, or crepey skin sitting on top of it. PDGF+® works on that layer directly.

Product Spotlight

Alastin® ReSURFACE Skin Polish

ReSURFACE is a dual-action exfoliating skin polish that gently helps remove dead cells and impurities without stripping the skin. Your skin instantly feels smoother, softer, and visibly brighter. Dual action exfoliation powered by volcanic minerals and glycolic acid (AHA) to remove dead skin cells and uncover visibly glowing skin.

“I love this product for an instant glow. Used 1-2 times per week, in addition to your skincare regimen, it brightens dullness. It is suitable for most skin types and concerns. With a 30-second application, your skin will be visibly softer and more supple.” – Kimberly, Licensed Medical Aesthetician

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Ask the Surgeon

If you have questions you would like Dr. Gregg to answer, please email them to info@cynthiagreggmd.com, and we will include them in a future Ask The Surgeon Column.

Q: I have been using GLP-1 for weight loss, and I am concerned about the sagging and wrinkles appearing on my face. I am really unhappy with my appearance due to this and want to know if there is anything that can be done to make my face look fuller/healthier?

A: We do have some options for treating these signs of facial aging.

The use of glucagon-like peptide-1 receptor agonists, such as semaglutide (Wegovy, Ozempic), tirzepatide (Mounjaro, Zepbound), and liraglutide (Victoza), is expected to continue to grow in the US. Currently, up to 12% of Americans report using a GLP-1 for weight loss.

The desired weight loss achieved by patients on GLP-1s is often accompanied by an increase in their facial aging due to volume loss and increased sagging and wrinkling in the skin. This appearance has been called “Ozempic Face.”

Studies are now confirming what clinicians have long noted: the resulting facial aging is not just due to loss of volume in the face, but also to accelerated skin aging. This increased skin aging is attributed to a decrease in the dermal white adipose tissue (DWAT). This superficial layer of adipose tissue can compromise up to 10-20% of the total body weight in lean adults, with the thickness of the layer varying across different regions of the body. Studies suggest that this fat layer is a significant source of adipose-derived stem cells (ADSC). ADSCs play a crucial role in skin regeneration by secreting various essential growth factors and peptides. The possible depletion of this DWAT layer may lead to the reduction of skin integrity by negatively affecting skin rejuvenation.

Treatment of the facial changes that occur with the use of GLP-1s should not only replace volume loss but also target the stimulation of ADSCs in this fat layer. Non-surgical treatments to address this include dermal fillers, biostimulator injectables microneedling, and PDGF+. Those procedures can not only add volume but also stimulate the ADSCs to release growth factors, helping to rejuvenate the skin. PDGF+ placed in the dermis is another way to increase the concentration of growth factors to achieve facial skin rejuvenation.

Studies show that injecting fat in the form of Nanofat is a surgical option to stimulate the creation of new collagen and elastin, leading to improved skin texture, reduced wrinkles, and a rejuvenated appearance. Nanofat is an emulsified microfat harvested from the inner thigh or abdomen and processed in a sterile manner before being injected under the facial skin. Because it is derived from the patient’s own body, it is biocompatible, reducing the risk of allergic reactions and providing a natural-looking result. Additionally, surgical procedures such as a lower facelift or necklift can help improve facial appearance by repositioning and removing any skin and muscle laxity that occurs after weight loss.

Each patient has unique facial anatomy and skin quality. For a patient seeking to reduce the facial aging effects of rapid weight loss, a thorough assessment is needed to determine which option can help meet their aesthetic goals. Our Aesthetic Nurse Injectors are all highly experienced in working with patients who want to address the effects of the “Ozempic Face” to restore their appearance. Call our office or use the Appointment Request Form on our website to schedule a consultation with one of our Aesthetic Nurse Injectors to begin your journey in eliminating the visible effects of rapid weight loss. Should they determine that non-surgical methods will not successfully address your concerns, they will refer you to me to discuss surgical intervention.

– Cynthia Gregg, MD, FACS

"Kimberly was incredibly professional, knowledgeable, and made me feel completely comfortable during my Diamond glow treatment. She took the time to customize the facial for my skin type. My skin continued to feel hydrated and refreshed after the appointment. The service was excellent from start to finish."

- S.D.

Client Testimonials

"Delighted with the results of my surgery and received great care from Dr. Gregg and her team throughout, from first consult to 3 months post-op. If you're wanting beautiful, natural, unnoticeably noticeable results, I can't recommend Dr. Gregg more highly. She's an artist!"

- A.Z.

Client Testimonials

"I have been a client of Cynthia Gregg MD for over 10 years. Nena Christoff has been my aesthetician specifically, there are no words to express what she had done for me personally, her caring professional demeanor and just being the delightful person she is has kept me going back over and over during these years, she is like family and she has made me feel and look beautiful!"

- K.G.

Client Testimonials

"I am so pleased with Megan Berrio RN at Dr. Cynthia Gregg office. I've had a number of injectables with Megan. She is always so gentle and caring. And she has a wonderful personality. I've always left the office very happy with the outcome."

- N.J.

Client Testimonials

"I cannot say enough good things about Andrea! She really listened to what my goals were, and what I wanted to accomplish and any concerns I had. She is wonderful at what she does, and cannot recommend her more!"

- M.G.